Method of screening for drug hypersensitivity reaction

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United States of America Patent

PATENT NO 7858319
SERIAL NO

12428034

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods of assessing the risk of clinical signs of hypersensitivity reaction to nucleoside antiviral compounds, including abacavir, are described. The methods include genotyping subjects for polymorphisms in the TNF.alpha. gene, the class 1 HLA genes, or a combination of both the TNF.alpha. and HLA genes.

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Patent Owner(s)

Patent OwnerAddress
VIIV HEALTHCARE U K LIMITED980 GREAT WEST ROAD BRENTFORD MIDDLESEX 19102

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hetherington, Seth Alpharetta, US 2 3
Hughes, Arlene R Durham, US 3 20
Lai, Eric H Durham, US 5 62
Mosteller, Michael Jr Durham, US 2 3
Shortino, Denise D Durham, US 2 3

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