Method of stabilizing proteins
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United States of America Patent
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Dec 28, 2010
Grant Date -
Oct 18, 2007
app pub date -
May 27, 2005
filing date -
Jun 1, 2004
priority date (Note) -
Expired
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Abstract
A method of preparing a stabilized bulk solution of a monomeric protein is described, which consists in providing a bulk of monomeric protein in a buffer solution and adding an excipient to the bulk, wherein the excipient is selected from the group consisting of bacteriostatic agents, surfactants, isotonicity agents, amino acids, antioxidants and combinations thereof. Prefereably the monomeric protein is IFN-beta.
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