Materials and methods for treatment of cancer
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United States of America Patent
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Dec 21, 2010
Grant Date -
Oct 2, 2008
app pub date -
Mar 22, 2005
filing date -
Mar 22, 2004
priority date (Note) -
Expired
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Abstract
Glypican 5 is shown for the first time to have a role in proliferation of cancer cells, including tumors which do not show chromosomal amplification at 13q31. The use of glypican 5 (GPC5) antagonists and binding agents for the treatment of cancer, particularly rhabdomyosarcoma and breast cancer, is disclosed.
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