Comparative multidimensional gel electrophoresis
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United States of America Patent
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Dec 21, 2010
Grant Date -
Jul 5, 2007
app pub date -
Dec 20, 2006
filing date -
Dec 21, 2005
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Abstract
A device providing an arrangement for the separation of a sample mixture for analytical reasons based on multidimensional gel electrophoresis and method thereof are disclosed. The separation involves a first separation in a first dimension of the device on the basis of isoelectric points and a second separation in a second dimension of the device on the basis of molecular size. At least two gel strips for the first dimension separation step and a corresponding gel for the second dimension separation step are provided. The two gel strips are arranged on a single carrier either on the same side or on opposite sides. By having at least two gel strips arranged in such a manner at least two analytical processes can be executed in parallel on the single carrier without the use of valves.
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