Susceptibility gene for myocardial infarction, stroke, and PAOD; methods of treatment
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United States of America Patent
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Dec 14, 2010
Grant Date -
May 26, 2005
app pub date -
Apr 22, 2004
filing date -
Oct 17, 2002
priority date (Note) -
Expired
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Abstract
Linkage of myocardial infarction (MI) and a locus on chromosome 13q12 is disclosed. In particular, the FLAP gene within this locus is shown by genetic association analysis to be a susceptibility gene for MI and ACS, as well as stroke and PAOD. Pathway targeting for treatment and diagnostic applications in identifying those who are at risk of developing MI, ACS, stroke or PAOD, in particular are described.
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