Dipiperazinyl ketones and related analogues
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United States of America Patent
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Dec 14, 2010
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app pub date -
Jul 28, 2006
filing date -
Aug 2, 2005
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Abstract
Dipiperazinyl ketones and related analogues are provided, as are methods for their preparation and use. Such compounds may generally be used to modulate ligand binding to histamine H3 receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and therapeutic methods are provided, as are methods for using such ligands for detecting histamine H3 receptors (e.g., receptor localization studies).
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