Biosynthetic gene cluster for leptomycins
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Dec 14, 2010
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Aug 24, 2007
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Sep 11, 2003
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Abstract
Polypeptides and domains of leptomycin polyketide synthase and the nucleic acids encoding them are provided. Methods to prepare leptomycin, leptomycin analogs, and leptomycin derivatives are described, as are methods to prepare other polyketides using the nucleic acids encoding leptomycin polyketide synthase domains or modifying enzymes.
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