Pyridine methylene azolidinones and use thereof phosphoinositide inhibitors
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Nov 30, 2010
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Sep 2, 2005
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Sep 3, 2004
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Abstract
The present invention relates to pyridine methylene azolidinone compounds of Formula (I)for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, allergy, asthma, pancreatitis, multi-organ failure, kidney diseases, platelet aggregation, cancer, sperm motility, graft rejection or lung injuries. Specifically, the present invention is related to pyridine methylene azolidinone derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide-3-kinases, PI3Ks.
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