Substituted piperazines

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United States of America Patent

PATENT NO 7842693
SERIAL NO

10732897

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Compounds are provided that act as potent antagonists of the CCR1 receptor, and which have been further confirmed in animal testing for inflammation, one of the hallmark disease states for CCR1. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.

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Patent Owner(s)

Patent OwnerAddress
CHEMOCENTRYX INC850 MAUDE AVENUE MOUNTAIN VIEW CA 94043

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aggen, James B Burlingame, US 19 392
Dairaghi, Daniel Joseph Palo Alto, US 8 222
Martichonok, Valeri V San Francisco, US 3 15
McMaster, Brian E Mountain View, US 18 476
Pennell, Andrew M K San Francisco, US 38 555
Sen, Subhabrata Sunnyvale, US 132 2469
Wright, J J Kim Redwood City, US 8 55

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