Method for preventing or treating cardiac hypertrophy
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United States of America Patent
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Nov 23, 2010
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app pub date -
Jun 14, 2005
filing date -
Jun 14, 2004
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Abstract
A method for treating or preventing cardiac hypertrophy in a mammal, comprising manipulating levels of RBP, retinoids, or an affiliated signaling and regulatory pathway in the mammal. Preferably, the method comprises reducing or inhibiting the level of RBP or retinoids or their signaling pathway, or an affiliated signaling pathway, via a dietary, genetic, protein-based, or pharmacologic approach, or a combination thereof. Also disclosed are pharmaceutical composition suitable for the method.
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