Triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7829724
SERIAL NO

11502473

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention provides novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors according to formula (I) that are useful in the treatment or prophylaxis of physiological and/or pathophysiological conditions in mammals, preferably humans, that are mediated by GHS receptors. The present invention further provides GHS receptor antagonists and agonists that can be used for modulation of these receptors and are useful for treating above conditions, in particular growth retardation, cachexia, short-, medium- and/or long term regulation of energy balance; short-, medium- and/or long term regulation (stimulation and/or inhibition) of food intake; adipogenesis, adiposity and/or obesity; body weight gain and/or reduction; diabetes, diabetes type I, diabetes type II, tumor cell proliferation; inflammation, inflammatory effects, gastric postoperative ileus, postoperative ileus and/or gastrectomy (ghrelin replacement therapy).

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
ZENTARIS GMBHWEISMULLERSTRASSE 50 FRANKFURT 60314
LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUERUE MICHEL ANGE PARIS CEDEX 16 F-75794
UNIVERSITY OF MONTPELLIER IICASE COURRIER 406 PLACE EUGENE BATAILLON MONTPELLIER CEDEX 5 34095
UNIVERSITY OF MONTPELLIER 15 BD HENRI IV BP 107 34006 MONTPELLIER CEDEX 5

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boeglin, Damien Eguisheim, FR 7 64
Demange, Luc Orsay, FR 5 62
Fehrentz, Jean-Alain St. Nazaire de Pezan, FR 7 57
Martinez, Jean Caux, FR 43 206
Moulin, Aline Portes-les-Valence, FR 5 67
Perrissoud, Daniel Bad Homburg, DE 4 70

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation