Pyrimidine derivatives for the treatment of abnormal cell growth
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United States of America Patent
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Oct 26, 2010
Grant Date -
Sep 25, 2008
app pub date -
Dec 20, 2006
filing date -
Dec 21, 2005
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Expired
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Abstract
The present invention relates to a compound of the formula 1or a pharmaceutically acceptable salt thereof, wherein Ar is a group of formula, M, Q, W, X, m, p and q are as defined herein. Such novel pyrimidine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
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