-derived vaccine and therapy against botulism

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United States of America Patent

PATENT NO 7820411
SERIAL NO

12040542

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Abstract

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transformed with an expression vector comprising DNA encoding HCR protein, (b) inducing expression of the HCR protein at a reduced temperature in a culture media, and (c) purifying the HCR protein via extraction, wherein the extraction comprises a clarification by centrifugation and a filtration, wherein the purified HCR protein is at least 10 mg/L of culture medium.

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Patent Owner(s)

Patent OwnerAddress
WISCONSIN ALUMNI RESEARCH FOUNDATION614 NORTH WALNUT STREET MADISON WISCONSIN 53705-7365
MCW RESEARCH FOUNDATION8701 WATERTOWN PLANK ROAD MILWAUKEE WI 53226

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baldwin, Michael Milwaukee, US 21 179
Barbieri, Joseph T Milwaukee, US 13 54
Bradshaw, Marite Madison, US 17 136
Johnson, Eric A Madison, US 106 3353
Pier, Christina L Fitchburg, US 3 8
Tepp, William H Stoughton, US 13 128

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