Predicting hepatotoxicity using cell based assays

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United States of America Patent

PATENT NO 7817840
APP PUB NO 20060234332A1
SERIAL NO

11375541

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Cell based assays are used to assess the hepatotoxicity of a stimulus. Imaging technologies are used to analyze the effects of a stimulus on hepatocytes. Image analysis may characterize the stimulus on the basis of whether it is hepatotoxic, and if so what type of pathology is exhibited; e.g., apoptosis, necrosis, cholestasis, and/or steatosis.

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Patent Owner(s)

Patent OwnerAddress
CYTOKINETICS INCSOUTH SAN FRANCISCO CA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adams, Cynthia Lynn San Carlos, US 6 45
Fan, Jinhong San Mateo, US 14 85
Mattheakis, Larry C Cupertino, US 39 878
Rao, Aibing Burlingame, US 9 68
Solar, Gregg Peter San Anselmo, US 4 36
Trautman, Jay Kenneth Los Altos, US 9 134
Vaisberg, Eugeni Foster City, US 7 46

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