Fluorescence tomography using line-by-line forward model

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United States of America Patent

PATENT NO 7812945
APP PUB NO 20080312879A1
SERIAL NO

11764041

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A fluorescence optical tomography system and method uses a photon migration model calculator for which absorption and reduced scattering coefficient values are determined for each source/detector pair. The coefficient values may be determined by measurement, in which a time resolved detector detects the excitation wavelength and generates temporal point spread functions from which the coefficient values are found. Alternatively, the coefficient values may be determined by calculating them from a dataset containing a spatial distribution of absorption and reduced scattering coefficients in a volume of interest. The fluorescence detection may be continuous wave, time resolved, or a combination of the two. An estimator uses a detected fluorescence signal and an estimated fluorescence signal to estimate the image values.

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Patent OwnerAddress
SOFTSCAN HEALTHCARE GROUP LTDROAD TOWN TORTOLA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fortier, Simon Montreal, CA 3 15
Leblond, Frederic Montreal, CA 21 272

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