Manufacture of pure hydralazine salts

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United States of America Patent

PATENT NO 7807830
APP PUB NO 20090187018A1
SERIAL NO

12418354

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Abstract

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The present invention provides an improved process of preparing hydralazine hydrochloride, which involves the preparation of 1-chlorophthalazine salt and further reacting with hydrazine followed by purification of hydralazine hydrochloride, which is free of phosphate, does not contain any individual impurities more than 0.05%, total impurities less than 0.5%, and a hydrazine content of not more than 0.001%, and preferably less than 0.0003%. One benefit of improved purity is enhanced storage stability.

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Patent OwnerAddress
NAVINTA LLCEWING NJ 08618-1414

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jobdevairakkam, Christopher N Plainsboro, US 11 92
Kannappan, Jayaraman Gujrat, IN 20 2
Rangisetty, Jagadeesh B Hyderabad, IN 4 0

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges6001518335120544124151144601 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +01002003004005006007008009001000110012001300140015001600

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