Use of a nucleic acid/PEI complex
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United States of America Patent
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Sep 14, 2010
Grant Date -
May 12, 2005
app pub date -
Sep 21, 2001
filing date -
Sep 22, 2000
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Expired
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Abstract
The invention concerns the use of a nucleic acid/cationic polymer complex, preferably polyethyleneimine (PEI) for preparing a composition for intraventricular stereotactic screening of stem cells of the brain for preparing a medicine for treating neurodegenerative and/or demyelinating disease. The invention further concerns a method for obtaining an animal whereof the genome of stem cells of the brain are modified by using said complex. The invention also concerns a method for obtaining an animal for screening compounds designed to modify the disposition of stem cells of the brain.
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