Macrolide compound in solid form, process for preparation thereof, and pharmaceutical composition containing the same
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United States of America Patent
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Sep 7, 2010
Grant Date -
Sep 4, 2008
app pub date -
Jan 28, 2008
filing date -
Jan 29, 2007
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention provides the compound of formula (I) in a solid form which, as a bulk medicament for pharmaceutical manufacture, is uniform, has a high purity, and is easy to work with. The invention further provides a process for preparing this compound, and pharmaceutical compositions containing the same. A solid form of (8E,12E,14E)-7-{(4-cycloheptylpiperazin-1-yl)carbonyl}oxy-3,6,16,21-tetrahydroxy-6,10,12,16,20-pentamethyl-18,19-epoxytricosa-8,12,14-trien-11-olide which has uniform specifications and is easy to work with was developed.
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