Preparation of human, humanized or chimaeric antibodies or polypeptides having different binding profiles to Fcgamma receptors
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United States of America Patent
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Sep 7, 2010
Grant Date -
Jun 14, 2007
app pub date -
Apr 5, 2004
filing date -
Apr 3, 2003
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Expired
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Abstract
The present invention relates to a method for the production and the selection of human or chimæric or humanized antibodies or molecules that comprise the Fc region of human IgG, capable of modulating the activity of one or several particular Fc receptors, such as the triggering of inhibitory functions through the human type IIB receptors of IgG (FcgammaRIIB/CD32).
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