NANBV diagnostics and vaccines

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7790366
SERIAL NO

08441443

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A family of cDNA sequences derived from hepatitis C virus (HCV) are provided. These sequences encode antigens which react immunologically with antibodies present in individuals with non-A non-B hepatitis (NANBH), but which are absent from individuals infected with hepatitis A virus, or hepatitis B virus, and also are absent in control individuals. The HCV cDNA sequences lack substantial homology to the sequences of hepatitis delta virus (HDV) and HBV. A comparison of the sequences of amino acids encoded in the HCV cDNA with the sequences of Flaviviruses indicates that HCV may be related to the Flaviviruses.The HCV cDNA sequences and the polypeptides encoded therein are useful as reagents for the detection and therapy of HCV. The reagents provided in the invention are also useful for the isolation of NANBH agent(s), for the propagation of these agents in tissue culture, and for the screening of antiviral agents for HCV.

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Patent Owner(s)

Patent OwnerAddress
NOVARTIS VACCINES AND DIAGNOSTICS INC4560 HORTON STREET EMERYVILLE CA 94608
GRIFOLS WORLDWIDE OPERATIONS LIMITEDGRANGE CASTLE BUSINESS PARK GRANGE CASTLE CLONDALKIN DUBLIN 22

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Choo, Qui-Lim El Cerrito, US 53 1206
Houghton, Michael Danville, US 164 2818
Kuo, George San Francisco, US 50 1383

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  • 15 Citation Count
  • A61K Class
  • 66.62 % this patent is cited more than
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges7303334104243222310478582826113401 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +020040060080010001200140016001800200022002400260028003000320034003600

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