Fiber optic device for sensing analytes and method of making same
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United States of America Patent
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Aug 31, 2010
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app pub date -
Oct 19, 2004
filing date -
Nov 26, 2003
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Abstract
A device for sensing analyte concentration, and in particular glucose concentration, in vivo or in vitro is disclosed. A sensing element is attached to the distal end of an optical conduit, and comprises at least one binding protein adapted to bind with at least one target analyte. The sensing element further comprises at least one reporter group that undergoes a luminescence change with changing analyte concentrations. Optionally, the optical conduit and sensing element may be housed within a cannulated bevel.
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