)one derivatives
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United States of America Patent
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Aug 24, 2010
Grant Date -
Oct 30, 2008
app pub date -
May 14, 2008
filing date -
Sep 21, 2001
priority date (Note) -
Expired
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Abstract
The invention relates to use of a pyrimidone derivative represented by formula (I) or a salt thereof as therapeutic agents:Wherein m, n, p, X, Y, R1, R2, R3, R4 R5, are as defined herein. The invention specifically relates to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3β or GSK3β and cdk5/p25, such as Alzheimer disease.
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