GPCR-expressing cell lines
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United States of America Patent
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Aug 24, 2010
Grant Date -
Aug 23, 2007
app pub date -
Sep 29, 2006
filing date -
Sep 25, 2005
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Abstract
The present invention provides expression vectors that facilitate high levels of expression of GPCR proteins. Encompassed by the invention are methods and compositions for recombinant cell lines expressing GPCR proteins with the aid of the expression vectors of the instant invention. The recombinant cell lines of the instant invention express GPCR proteins at levels of at least about 150,000 copies of the protein per cell. The present invention also provides methods and compositions for raising antibodies against GPCR proteins using the high expressing recombinant cells of the instant invention.
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