Peroxisome proliferation activated receptor alpha (PPARα) signatures
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United States of America Patent
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Aug 17, 2010
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N/A
app pub date -
Dec 16, 2003
filing date -
Dec 17, 2002
priority date (Note) -
Expired
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Abstract
The present invention includes methods and apparatus for use in rapid testing for and prediction of a PPARα response (i.e. a response similar to that of PPARα agonists). The invention includes a PPARα response signature comprising a set of twenty genes. The invention discloses methods whereby the differential expression of the genes of the PPARα response signature may be used to predict whether a compound will induce a PPARα response in a test subject.
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