Neural regeneration peptides and methods for their use in treatment of neural injury or degeneration
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United States of America Patent
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Aug 3, 2010
Grant Date -
Nov 13, 2003
app pub date -
Aug 22, 2002
filing date -
Aug 24, 2001
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Abstract
The invention discloses a family of neuronal migration-inducing, proliferation-promoting and neurite outgrowth promoting factors, termed NRP compounds, and provides compositions and methods for the use of NRP compounds in the treatment of brain injury and neurodegenerative disease. NRP compounds induce neurons and neuroblasts to proliferate and migrate into areas of damage caused by acute brain injury or chronic neurodegenerative disease, such as stroke, trauma, nervous system infections, demyelinating diseases, dementias, and metabolic disorders. NRP compounds may be administered directly to a subject or to a subject's cells by a variety of means including orally, intraperitoneally, intravascularly, and directly into the nervous system of a patient.
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