Method preparation clopidogrel and intermediates used therein
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United States of America Patent
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Jul 27, 2010
Grant Date -
Dec 24, 2009
app pub date -
Aug 28, 2009
filing date -
Jun 23, 2005
priority date (Note) -
Expired
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Abstract
Optically pure clopidogrel can be prepared in a high yield by optically resolving a racemic form of the compound of formula (II) using an optically active amine to form the optically active form of the compound of formula (III) or its acid-addition salt; and methylating the compound of formula (III) or its acid-addition salt.
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