Method for producing non-hydrated fexofenadine hydrochloride and a novel crystalline form obtained thereby
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United States of America Patent
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Jul 20, 2010
Grant Date -
Jul 28, 2005
app pub date -
Jan 17, 2002
filing date -
Feb 23, 2001
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Abstract
The invention relates to non-hydrated fexofenadine hydrochloride which can be obtained from a fexofenadine base and hydrogen chloride, according to the reaction conditions, either in the form of a novel polymorph (“form A”), in an amorphous form, or in the form of a mixture of different polymorphs. Said novel polymorph (“form A”) can be used as a therapeutic active ingredient and can be processed to form a pharmaceutical containing the same and a pharmaceutically acceptable carrier. Said pharmaceutical is suitable for use as an antihistaminic agent, an antiallergic agent and/or a bronchodilating agent.
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