Composition exhibiting enhanced formulation stability and delivery of topical active ingredients
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United States of America Patent
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Jul 20, 2010
Grant Date -
May 30, 2002
app pub date -
Oct 23, 2001
filing date -
Apr 21, 2000
priority date (Note) -
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Abstract
A therapeutic, cosmetic or cosmeceutic composition for topical application, capable of stabilizing an active ingredient and delivering the active ingredient, comprising a plurality of microcapsules having a core-shell structure. The microcapsules have a diameter of approximately 0.1 to 100 micron. The core of each microcapsule includes at least one active ingredient and is encapsulated within a microcapsular shell. The shell is comprised of at least one inorganic polymer obtained by a sol-gel process, and the shell protects the active ingredient before topical application and is designed to release the active ingredient from the microcapsules following application. The composition is useful in encapsulating active ingredients, such as benzoyl peroxide, that are unstable in other formulation, or are irritating to the skin.
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