Non-nucleotide compositions and method for treating pain

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United States of America Patent

PATENT NO 7749980
APP PUB NO 20070123544A1
SERIAL NO

10576859

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention is directed to a method of treating pain. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a P2X receptor antagonist. The methods of the present invention are useful in reducing pain, such as traumatic pain, neuropathic pain, organ pain and/or pain associated with diseases. The P2X receptor antagonists useful for this invention are non-nucleotide compounds of general Formula I. Compounds of Formula I can be used alone to treat pain. Compounds of Formula I can also be used in conjunction with other therapeutic agents or adjunctive therapies commonly used to treat pain, thus enhancing the therapeutic effect of pain reduction.

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Patent Owner(s)

Patent OwnerAddress
INSPIRE PHARMACEUTICALS INC4222 EMPEROR BLVD SUITE 200 DURHAM NC 27703

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abreo, Melwyn Anthony Jamul, US 2 34
Alfaro-Lopez, Lorenzo Josue San Marcos, US 4 32
Crean, Christopher S Pittsboro, US 14 174
Feng, Yangbo Palm Beach Gardens, US 24 104
Holladay, Mark W San Diego, US 51 756
Khasanova, Tatyana V San Diego, US 3 36
Plourde,, Jr Robert Chapel Hill, US 5 23
Shaver, Sammy R Chapel Hill, US 28 254

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