Methods of gene transfer to astrocytes with mokola virus pseudotyped lentivirus vectors
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United States of America Patent
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Jul 6, 2010
Grant Date -
Jun 24, 2004
app pub date -
May 31, 2002
filing date -
Jun 1, 2001
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Abstract
The invention relates to a defective lentivirus which is pseudotyped with a lyssavirus envelope of the PV (rabies virus) or MOK type (Mokola virus), for example, and to the use thereof, especially in the preparation of a composition for in vivo transfer of genes in astrocytes and also for the treatment of disorders of the central nervous system.
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