Methods and apparatus for sorting cells using an optical switch in a microfluidic channel network
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United States of America Patent
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Jun 29, 2010
Grant Date -
Sep 22, 2005
app pub date -
Aug 27, 2004
filing date -
Aug 28, 2003
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Abstract
Apparatus and Methods are provided for a microfabricated fluorescence activated cell sorter based on an optical switch for rapid, active control of cell routing through a microfluidic channel network. This sorter enables low-stress, highly efficient sorting of populations of small numbers of cells (i.e., 1000-100,000 cells). The invention includes packaging of the microfluidic channel network in a self-contained plastic cartridge that enables microfluidic channel network to macro-scale instrument interconnect, in a sterile, disposable format.
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