Process for the biological production of 1,3-propanediol with high yield
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United States of America Patent
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Jun 29, 2010
Grant Date -
Jul 24, 2008
app pub date -
Mar 24, 2008
filing date -
Oct 4, 2002
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Abstract
The present invention provides a microorganism useful for biologically producing 1,3-propanediol from a fermentable carbon source at higher yield than was previously known. The complexity of the cofactor requirements necessitates the use of a whole cell catalyst for an industrial process that utilizes this reaction sequence to produce 1,3-propanediol. The invention provides a microorganism with disruptions in specified genes and alterations in the expression levels of specified genes that is useful in a higher yielding process to produce 1,3-propanediol.
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