Plasmon resonance biosensor and method
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United States of America Patent
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Jun 29, 2010
Grant Date -
Jun 22, 2006
app pub date -
Nov 18, 2005
filing date -
Nov 19, 2004
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Abstract
A method of analyzing a sample comprising directing a beam of light to a spot on the surface of a microarray treated with the sample using a digital micromirror device, and observing the SPR spectral shift due to a chemical binding event. The digital micromirror device can be, for example, that used in Digital Light Processing (DLP). Such a device can selectively place a pixel of light onto a microarray such that each spot can be observed at millisecond intervals and the whole microarray can be sequentially scanned over a relatively short period. The SPR spectral shift for each spot can be measured as a function of time, thus producing SPR detection of molecular binding in an array format.
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