System for detecting polynucleotides

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United States of America Patent

PATENT NO 7745119
APP PUB NO 20060147958A1
SERIAL NO

11285025

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to methods for detecting the presence or amount of a target polynucleotide. A polynucleotide, target nucleic acid analog, and dye are combined to form a mixture. The optical property of the dye is observed after the mixture is exposed to a stimulating means. Optionally, after the stimulating means is employed, the mixture is compared to a reference value characteristic of the rate of change in the optical property of the dye in a similar mixture containing a known amount of a target polynucleotide/nucleic acid analog hybrid to determine a relative rate of change in the optical property. The change in a property of the mixture after exposure thereof to a stimulating means or the relative rate of change in the optical property of dye in the mixture is correlated with the presence or amount of the specified target polynucleotide in the sample.

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Patent Owner(s)

Patent OwnerAddress
INVESTIGEN750 ALFRED NOBEL DRIVE HERCULES CA 94547-1805

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Choi, K Yeon St. Paul, US 6 249
Koshinsky, Heather El Cerrito, US 16 136
Zwick, Michael S Vacaville, US 4 193

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