Fusion constructs containing active sections on TNF ligands
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United States of America Patent
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Jun 15, 2010
Grant Date -
Jul 14, 2005
app pub date -
Aug 21, 2002
filing date -
Feb 10, 2002
priority date (Note) -
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Abstract
Disclosed is a recombinant fusion protein containing an amino-acid sequence which comprises: (a) the Fc section or part of an Fc section of an immunoglobulin as component (A) or a functional variant of component (A); (b) the extracellular part of a TNF ligand or a partial sequence of the extracellular part of a TNF ligand as component (B) or a functional variant of component (B); and optionally (c) a transition area between component (A) and component (B), containing a linker.
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