Protozoan strains of reduced virulence and use thereof

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United States of America Patent

PATENT NO 7732188
SERIAL NO

10577560

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Abstract

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The present invention relates to a protozoan strain of the family of the Trypanosomatidae the virulence of which is lower than that of the corresponding wild-type strain, characterized in that at least one copy of the SIR2 gene present in the genome of the strain is inactivated.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSIDADE DO PORTO4099-002 PORTO
INSTITUT DE RECHERCHE POUR LE DEVELOPMENT213 RUE LA FAYETTE F-75480 PARIS CEDEX 10

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cordeira, Da Silva Anabela Oporto, PT 1 28
Ouaissi, Ali La Boissiere, FR 2 28
Sereno, Denis Poussan, FR 9 35
Vergnes, Baptiste Montpellier, FR 2 28

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