Recombinant methods and materials for producing epothilone and epothilone derivatives
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United States of America Patent
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Jun 8, 2010
Grant Date -
Jul 2, 2009
app pub date -
Oct 31, 2007
filing date -
Nov 20, 1998
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Abstract
Recombinant nucleic acids that encode all or a portion of the epothilone polyketide synthase (PKS) are used to express recombinant PKS genes in host cells for the production of epothilones, epothilone derivatives, and polyketides that are useful as cancer chemotherapeutics, fungicides, and immunosuppressants.
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