Non-sedating barbiturate compounds as neuroprotective agents
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United States of America Patent
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May 25, 2010
Grant Date -
Sep 14, 2006
app pub date -
Feb 16, 2006
filing date -
Jul 26, 2000
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Expired
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Abstract
Methods of providing neuroprotection are disclosed comprising administering a non-sedative barbiturate compound in an amount sufficient to achieve neuroprotection in a mammalian subject. Preferred compounds are in the family of diphenylbarbituric acid and analogs. Preferred doses for a neuroprotective effect exceed the dosage of a corresponding sedative barbiturate without sedative side-effects such as anesthesia and death.
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