Interacting polypeptide comprising a heptapeptide pattern and a cellular penetration domain
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United States of America Patent
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May 4, 2010
Grant Date -
Oct 26, 2006
app pub date -
Mar 30, 2006
filing date -
Sep 30, 2003
priority date (Note) -
Expired
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Abstract
is located between 5 and 35 amino acids of the C-terminal end of said polypeptide, and that the domain (b) is situated in C-terminal relative to pattern (a). The invention also relates to screening methods for identifying interacting polypeptides capable of modifying the phenotype of a cell and to uses of interacting polypeptides as mentioned in phenotypic screens or for therapeutic purposes. Lastly, the invention concerns interacting polypeptides capable of modifying the function of the HIV-1 Rev viral protein.
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