Methods for preventing or reducing ischemia/reperfusion induced myocardial cell death

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United States of America Patent

PATENT NO 7709216
APP PUB NO 20080009030A1
SERIAL NO

11891015

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided herein are methods relating to inhibition of PUMA function for preventing or reducing myocardial cell death. A method for preventing or reducing ischemia/reperfusion induced myocardial cell death in a human is provided as are methods for identifying pharmaceuticals which interfere with PUMA function. Also herein provided is a method for reducing stem cell death in stem cell explants wherein the explants are intended to restore cardiac efficiency following cell death in response to coronary infarct.

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Patent Owner(s)

Patent OwnerAddress
BOSTON BIOMEDICAL RESEARCH INSTITUTEBOSTON MA 02114

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Erhardt, Peter Natick, US 2 1
Toth, Ambrus Chestnut Hill, US 2 1

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