N-hydroxyamide derivatives possessing antibacterial activity
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United States of America Patent
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Apr 6, 2010
Grant Date -
Mar 6, 2008
app pub date -
Jul 11, 2003
filing date -
Jul 11, 2002
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Abstract
Novel N-hydroxyamide derivatives are disclosed. These N-hydroxyamide derivatives inhibit UPD-3-O—(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase, an enzyme present in gram negative bacteria and are therefore useful as antimicrobials and antibiotics. Methods of synthesis and of use of the compounds are also disclosed.
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