Method for treating diseases using HSP90-inhibiting agents in combination with antimitotics
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United States of America Patent
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Apr 6, 2010
Grant Date -
Jan 27, 2005
app pub date -
May 27, 2004
filing date -
May 30, 2003
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Expired
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Abstract
The present invention provides a method for treating cancer. The method involves the administration of an HSP90 inhibitor and an antimitotic, where the combined administration provides a synergistic effect. In one aspect of the invention, a method of treating cancer is provided where a subject is treated with a dose of an HSP90 inhibitor in one step and a dose of an antimitotic in another step. In another aspect of the invention, a method of treating cancer is provided where a subject is first treated with a dose of an HSP90 inhibitor and subsequently treated with a dose of an antimitotic. In another aspect of the invention, a method of treating cancer is provided where a subject is first treated with a dose of an antimitotic and subsequently treated with a dose of an HSP90 inhibitor.
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