Stable oxidation resistant powdered hemoglobin, methods of preparing same, and uses thereof
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United States of America Patent
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Mar 16, 2010
Grant Date -
Feb 14, 2008
app pub date -
Apr 20, 2005
filing date -
Apr 21, 2004
priority date (Note) -
Expired
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Abstract
The present invention provides oxygenated hemoglobins in powdered form and methods of preparing a powdered form of a protein, such as hemoglobin, which comprise (a) mixing a solution of the protein with inulin, and optimally with a reducing sugar such as glucose or tagatose, and (b) drying the mixture. Also provided are blood substitutes formed from reconstituted powdered hemoglobins, and methods of treatment using the blood substitutes.
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