ILK inhibitors for the treatment of renal disease
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United States of America Patent
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Mar 16, 2010
Grant Date -
Jan 3, 2008
app pub date -
Sep 14, 2007
filing date -
Nov 30, 2001
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Abstract
The invention relates to the treatment of renal diseases using modulators of integrin linked kinase. Methods of treatment as well as therapeutic agents including antisense, small molecules, catalytic peptides and antibodies are disclosed. The agents of the invention may also be used in combination with traditional therapies for renal disease including ACE inhibitors. An advantage of the invention is that it treats one of the causes of renal disease, rather than just ameliorating symptoms, and can help prevent the progression of renal disease to the point of acute renal failure.
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