Method for producing recombinant trypsin

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United States of America Patent

PATENT NO 7666629
APP PUB NO 20080064084A1
SERIAL NO

11853483

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Abstract

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which is soluble and secreted into the culture medium, whereby expression at pH 3.0-4.0 substantially prevents activation of trypsinogen to β-trypsin and autolysis of β-trypsin by α-trypsin into ε-trypsin and from there into inactive peptides.

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Patent Owner(s)

Patent OwnerAddress
ROCHE DIAGNOSTICS OPERATIONS INCINDIANAPOLIS INDIANA 46250

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Eckstein, Hellmut Weilheim, DE 5 22
Geipel, Frank Penzberg, DE 9 41
Giessel, Claudia Greiling, DE 9 30
Glaser, Stephan Seeshaupt, DE 8 40
Muller, Rainer Penzberg, DE 61 992
Ratka, Michael Mannheim, DE 2 9
Rexer, Bernhard Weilhem, DE 5 26
Ronning, Stephanie Penzberg, DE 3 15
Schneider, Claus Eppelheim, DE 63 383
Thalhofer, Johann-Peter Weilheim, DE 30 117

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