HIV vaccines based on Env of multiple clades of HIV
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United States of America Patent
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Feb 23, 2010
Grant Date -
Nov 20, 2008
app pub date -
Jun 13, 2007
filing date -
Sep 15, 2003
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Abstract
In one embodiment, the invention provides a multiclade HIV plasmid DNA or viral vector vaccine including components from different clades of Env (optionally Env chimeras) and Gag-Pol-(optionally)Nef from a single clade. The vaccine of the invention may further include V1, V2, V3, or V4 deletions or combinations thereof. In another embodiment, the invention provides multiclade HIV envelope immunogens.
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