Methods of treatment of autoimmune diseases using humanized immunoglobulin reactive with B7-2

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United States of America Patent

PATENT NO 7666421
APP PUB NO 20060251645A1
SERIAL NO

11294680

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Abstract

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The invention relates to a humanized anti-B7-2 antibody that comprises a variable region of nonhuman origin and at least a portion of an immunoglobulin of human origin. The invention also pertains to methods of treatment for various autoimmune diseases, transplant rejection, inflammatory disorders and infectious diseases by administering humanized anti-B7-2 and/or anti-B7-1 antibodies.

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Patent Owner(s)

Patent OwnerAddress
GENETICS INSTITUTE LLC87 CAMBRIDGEPARK DRIVE CAMBRIDGE MASSACHUSETTS 02140 UNITED STATES OF AMERICA

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Carreno, Beatriz Acton, US 12 168
Celniker, Abbie Cheryl Newton, US 7 121
Co, Man Sung Cupertino, US 25 3231
Collins, Mary Natick, US 65 2336
Goldman, Samuel Acton, US 20 303
Gray, Gary S Brookline, US 43 3533
Knight, Andrea Hampton, US 10 439
O'Hara, Denise Reading, US 14 389
Rup, Bonita Reading, US 7 121
Vasquez, Maximiliano Palo Alto, US 92 2096
Veldman, Geertruida M Sudbury, US 41 1935

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