Pteridinone derivatives for use as stearoyl CoA desaturase inhibitors

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United States of America Patent

PATENT NO 7662819
APP PUB NO 20080249100A1
SERIAL NO

11868407

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Abstract

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The present invention discloses pteridinone derivatives for use as inhibitors of stearoyl-CoA desaturase having the structure of Formula I:The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.

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Patent Owner(s)

Patent OwnerAddress
LIGAND PHARMACEUTICALS INCORPORATED3911 SORRENTO VALLEY BOULEVARD SUITE 110 SAN DIEGO CA 92121

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chisholm, Jeffrey Mountain View, US 8 207
Cole, Andrew Robbinsville, US 33 649
Glushkov, Andrey Moscow, RU 5 21
Henderson, Ian Hopewell, US 48 395
Koltun, Dmitry Foster City, US 50 601
Lin, Tsung Princeton, US 2 15
Parkhill, Eric San Francisco, US 16 334
Vasilevich, Natalya Moscow, RU 10 136
Zablocki, Jeff San Mateo, US 178 1806
Zilbershtein, Timur Kazan, RU 5 34

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