Method for identifying target epitopes of the T cell mediated immune response and for assaying epitope-specific T cells
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Feb 9, 2010
Grant Date -
May 26, 2005
app pub date -
Nov 20, 2002
filing date -
Nov 20, 2001
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
The present invention relates to a method for the detection of epitope-specific T-cells and target epitopes of reactive T-cells. Furthermore, the present invention relates to vectors comprising a first promoter which is specifically inducible by the epitope-specific contact with a T-cell in antigen-presenting cells, a nucleic acid which is functionally linked to this first promoter and which encodes a marker gene, a second promoter which is constitutive in antigen-presenting cells, and a nucleic acid which is functionally linked to said second promoter. Furthermore, the present invention relates to antigen-presenting cells which are transduced with the vectors according to the invention.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully