Nucleic acid purification method
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United States of America Patent
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Feb 2, 2010
Grant Date -
Mar 27, 2008
app pub date -
Sep 19, 2007
filing date -
Sep 26, 2006
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Abstract
Disclosed is a process for separating and/or purifying a nucleic acid by elution of the nucleic acid from anion exchange resins under conditions of high salt concentration and the presence in the eluant of an additive comprising guanidine, or a guanidine-like derivative. The process allows high recovery of nucleic acids from anion exchange resins without impairing the nucleic acid stability as compared with conventional ion exchange chromatographic procedures.
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